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KMID : 0359920080270030393
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Korean Journal of Nephrology
2008 Volume.27 No. 3 p.393 ~ p.396
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A Case of Acute Renal Infarction with Protein S Deficiency
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Kim Su-Ji
Hwang Soon-Oh
Kang Moon-Soo
Gil Hyo-Wook
Yang Jong-Oh
Lee Eun-Young
Hong Se-Yong
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Abstract
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Acute renal infarction is an uncommon disease that is often misdiagnosed initially because of its nonspecific presentation. Cardiovascular disease is the major cause of thromboembolic event, but renal infarction can also occur in patient with special conditions such as hypercoagulable states. Protein S deficiency is a rare cause of the hypercoagulable states and induces both venous and arterial thrombosis. Protein S are a vitamin K dependent plasma protein that serves as a cofactor for the anticoagulant effects of activated protein C. Patients deficient in protein S is prone to recurrent thromboembolic disease. We reported a case of acute renal infarction that was associated with type II protein S deficiency in a 38-year old patient without underlying cardiovascular disease.
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KEYWORD
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Infarction, Protein S deficiency, Thrombophilia
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